10676例泌尿生殖道感染门诊患者淋球菌、沙眼衣原体和解脲支原体感染分析

目的探讨2016年7月-2017年3月来上海某医院门诊就诊的10676例泌尿生殖道感染患者淋球菌(Neisseria gonorrhoeae,NG)、沙眼衣原体(Chlamydia trachomatis,CT)和解脲支原体(Ureaplasma urealyticum,UU)的感染分布情况。方法运用实时荧光定量PCR方法对10676例泌尿生殖道感染患者分别或同时进行NG、CT和UU测定。结果NG、CT和UU 3种病原体总检出率分别为1.47%、7.57%、71.27%,其中合并感染756例。检出率以21~30岁年龄段患者最高。在男性患者的样本中,CT的检出率为10.60%,UU的检出率为33.05%,NG的检出率为32.70%。在女性患者中,UU的检出率居首位,为72.16%,CT检出率为7.51%,NG检出率最低为0.89%。结论UU和NG的检出率具有明显的性别差异。随着患者年龄的增长,3种病原体检出的阳性样本数逐渐下降。

Analysis on Neisseria gonorrhoeae, Chlamydia trachomatis and Ureaplasma urealyticum infection in 10 676 outpatients with urogenital tract infection

Objective To explore the distribution of Neisseria gonorrhoeae(NG),Chlamydia trachomatis(CT)and Ureaplasma urealyticum(UU)infections in 10676 patients with urogenital tract infection who were admitted in clinic of a Shanghai hospital from July 2016 to March 2017.Methods NG,CT and UU were measured separately or simultaneously in 10676 patients with urogenital tract infection by real-time fluorescent quantitative PCR.Results The overall detection rates of 3 pathogens(NG,CT and UU)were 1.47%,7.57%and 71.27%,respectively,and 756 cases had a concurrent infection.The infection detection rate peaked in the patients aging 21-30 years old.In male patients,CT detection rate was 10.60%,UU detection rate was 33.05%and NG detection rate was 32.70%.In female patients,UU detection rate was highest,accounting for 72.16%,CT detection rate was 7.51%,and NG detection rate was lowest,accounting for 0.89%.Conclusions There are obvious gender differences in the detection rates of UU and NG,and the number of samples positive for three pathogens gradually decreases with the patient’s age.