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人类原始抗原(CD34)在毛发上皮瘤和基底细胞癌中的表达
引用本文:沈宏,张晴.人类原始抗原(CD34)在毛发上皮瘤和基底细胞癌中的表达[J].临床皮肤科杂志,1997,26(2):88-89.
作者姓名:沈宏  张晴
作者单位:杭州市第三医院皮肤科
摘    要:毛发上皮瘤是一种向毛囊分化的良性肿瘤,常与基底细胞癌混淆。应用人类原始抗原(CD34)检测7例毛发上皮瘤和12例基底细胞瘤中表达,结果:在正常皮肤血 皮细胞、血管周围和真皮内梭形细胞、毛囊、小汗腺周围梭形细胞阳性。毛发上皮瘤瘤团周围梭形细胞阳性,而基底细胞癌外周间质阴性,说明CD34染色有助于临别这两种肿瘤。

关 键 词:人类原始抗原  毛发上皮瘤  基底细胞瘤  皮肤肿瘤

CD 34 expression in trichoepitheliomas and Basal cell careinomas
Shen Hong,Zhang Qin,Shi Yuan,et al.CD 34 expression in trichoepitheliomas and Basal cell careinomas[J].Journal of Clinical Dermatology,1997,26(2):88-89.
Authors:Shen Hong  Zhang Qin  Shi Yuan  
Institution:Shen Hong,Zhang Qin,Shi Yuan,et al Department of Dermatology The 3rd,Hospital Hangzhou
Abstract:Trichoepithelioma(TE) is a benign skin tumor with follicular differentiation, which is frequently confused with basal cell carcinoma (BCC). We stained formalin fixed, paraffin embedded sections of 7 trichoepitheliomas and 12 basal cell carcinomas with CD 34 . Result: In the normal skin, CD 34 presence has been detected in endothelial cells,perimasccular/interstitial dendritic cells, perifolliculas area/around the eccrine glands of spindle shaped cells. The spindle shaped cells surrounding the islands of TE cells were focally strongly positive for CD 34 . In BCC,the stroma surrounding the nests of tumor cells were negative. The findings may prove to present diagnostic help in distinguishing these two tumors.
Keywords:CD    34    Trichoepithelioma  Basal cell carcinoma  
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