A comparative study of mismatch negativity (MMN) in epilepsy and non-epileptic seizures. |
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| Authors: | Nuri Gene-Cos Richard Pottinger Geoff Barrett Michael R Trimble Howard A Ring |
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| Institution: | Traumatic Stress Service, Clinical Treatment Center, Maudsley Hospital, London, UK. Nuri.Genecos@SLAM.nhs.uk |
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| Abstract: | This study investigated mismatch negativity (MMN) differences between subjects with non-epileptic seizures (NES), subjects with epilepsy, and healthy controls. Event-related potentials (ERPs) were obtained from 14 patients with NES, 15 patients with epilepsy and 16 healthy control subjects. A conventional MMN procedure was used with a random sequence of 12% deviant tones (922 Hz) and 88% standard tones (1000 Hz). Subjects were instructed to ignore the tones delivered through headphones whilst reading a book. Significant differences in distribution of the mismatch negativity (MMN) in patients with NES compared to controls were obtained (F3, p
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