| 氯吡格雷联合阿司匹林治疗急性心肌梗死的疗效研究 |
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| 引用本文： | 张攀,汪明慧. 氯吡格雷联合阿司匹林治疗急性心肌梗死的疗效研究[J]. 现代预防医学, 2011, 38(6): 1177-1178 |
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| 作者姓名： | 张攀 汪明慧 |
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| 作者单位： | 1. 华中科技大学同济医学院附属同济医院第二临床学院,武汉,530030
2. 河北保定二五二医院心内科 |
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| 摘 要： | [目的]探讨氯吡格雷联合阿司匹林治疗急性心肌梗死的疗效。[方法]将2009年10月～2010年10月对56例急性心肌梗死患者随机分为治疗组和对照组,各28例。在常规治疗的基础上,对照组给予阿司匹林治疗,治疗组给予阿司匹林+氯吡格雷治疗。比较两组临床疗效、血管再通率、再闭塞率、90d时左室射血分数(LVEF)、血小板聚集率和凝血指标。[结果]治疗组再闭塞率低于对照组,90d时LVEF高于对照组,差异有统计学意义(P﹤0.05);血管再通率高于对照组,但差异无统计学意义(P﹥0.05)。治疗组血小板聚集率低于对照组,差异有统计学意义(P﹤0.05),而凝血指标的变化两组间则无统计学差异。[结论]氯吡格雷联合阿司匹林治疗急性心肌梗死疗效优于单纯应用阿司匹林。
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| 关 键 词： | 氯吡格雷 阿司匹林 急性心肌梗死 疗效 |
CLINICAL EFFICACY OF CLOPIDOGREL COMBINED WITH ASPIRIN IN THE TREATMENT OF PATIENTS WITH ACUTE MYOCARDIAL INFARCTION |
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| ZHANG Pan,WANG Ming-hui. CLINICAL EFFICACY OF CLOPIDOGREL COMBINED WITH ASPIRIN IN THE TREATMENT OF PATIENTS WITH ACUTE MYOCARDIAL INFARCTION[J]. Modern Preventive Medicine, 2011, 38(6): 1177-1178 |
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| Authors: | ZHANG Pan WANG Ming-hui |
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| Affiliation: | ZHANG Pan,WANG Ming-hui.(The Affiliated Tongji Hospital,The Second Clinical College of Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China) |
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| Abstract: | [Objective]To explore the therapeutic effect and safety of clopidogrel combined with aspirin in patients with acute myocardial infarction.[Methods]56 patients suffering from acute myocardial infarction fom Oct 2009 to Oct 2010 in our hospital were randomly divided into treatment group and control group,with 28 patients in each group.The patients in the control group were treated with aspirin based on the standard therapy,while clopidogrel was added to the patients of the treatment group.We compared the reca... |
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| Keywords: | Clopidogrel Aspirin Acute myocardial infarction Therapeutic effect |
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