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3653例肺结核患者耐药性分析
引用本文:刘超群,刘艳科.3653例肺结核患者耐药性分析[J].现代预防医学,2011,38(4):725-727.
作者姓名:刘超群  刘艳科
作者单位:长沙市中心医院,长沙,410004
基金项目:国家十一五重大科技专项项目
摘    要:目的]了解长沙市中心医院结核菌耐药情况。方法]采用回顾性调查,对近7年3653例肺结核病人耐药性分析。结果]总耐药率39.3%,总耐多药率10.2%;初始耐药率37.5%,初始耐多药率6.8%;获得性耐药率47.5%,获得性耐多药率25.3%;耐药率由高到低为INH(23.2%),SM(18.5%),RFP(15.9%),EMB(15.1%),TH1321(13.9%),PZA(11.5%),PAS(8.3%),OFX(6.5%),KM(6.2%),LFX(2.2%)。结论]高耐药率以及耐药性趋向于一线抗痨药是长沙市中心医院结核菌耐药特征。

关 键 词:结核  耐药  抗结核药

ANALYSIS OF DRUG-RESISTANCE ON 3653 SAMPLE OF TUBERCULOSIS PATIENTS
LIU Chao-qun,LIU yan-ke.ANALYSIS OF DRUG-RESISTANCE ON 3653 SAMPLE OF TUBERCULOSIS PATIENTS[J].Modern Preventive Medicine,2011,38(4):725-727.
Authors:LIU Chao-qun  LIU yan-ke
Institution:LIU Chao-qun,LIU yan-ke.(The Center Hospital,Changsha 410004,China)
Abstract:Objective] To summarize current situation of mycobacterium tuberculosis drug resistance in Changsha Central Hospital.Methods] 3 653 sample of tuberculosis patients were performed drug resistance in the past 7 years.Results] Rate of total drug resistance was 39.3%,rate of total multidrug resistance was 10.2%,rate of initial drug resistance was 37.5%,rate of initial multidrug resistance was 6.8%,rate of acquired drug resistance was 47.5%,and rate of acquired multidrug resistance was 25.3%.The sequence of s...
Keywords:Tuberculosis  Drug-resistance  Antitubercular agents  
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