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郴州市2009年46例临床诊断为手足口病的病原学分析
引用本文:罗文英,谢群,朱伟民,陈白鹭,何清懿.郴州市2009年46例临床诊断为手足口病的病原学分析[J].现代预防医学,2011,38(6):1130-1131.
作者姓名:罗文英  谢群  朱伟民  陈白鹭  何清懿
作者单位:湖南省郴州市疾病预防控制中心分子生物学实验室,郴州,423000
摘    要:目的]了解2009年郴州市手足口病的病原体类型及分布特征。方法]采集46例临床诊断为手足口病病例的粪便样本,采用RT-PCR及Real-Time PCR法检测样本中的肠道病毒通用型(EV)、肠道病毒71型(EV71)、肠道病毒科萨奇A16型(CoxA16)3种核酸。结果]46例临床诊断手足口病样本,其中EV71型22例、通用型11例、CoxA16型4例,总阳性率为80.43%。结论]2009年引起郴州市重症手足口病的病原体主要为EV71型。

关 键 词:手足口病  病原学  肠道病毒属  逆转录聚合酶链式反应

ETIOLOGICAL ANALYSIS ON THE 46 CLINICALLY DIAGNOSED CASES WITH HAND-FOOT-MOUTH DISEASES IN CHENZHOU OF 2009
LUO Wen-ying,XIE Qun,ZHU Wei-ming,et al..ETIOLOGICAL ANALYSIS ON THE 46 CLINICALLY DIAGNOSED CASES WITH HAND-FOOT-MOUTH DISEASES IN CHENZHOU OF 2009[J].Modern Preventive Medicine,2011,38(6):1130-1131.
Authors:LUO Wen-ying  XIE Qun  ZHU Wei-ming  
Institution:LUO Wen-ying,XIE Qun,ZHU Wei-ming,et al.(Chenzhou Municipal Center for Disease Control and Prevention,Chenzhou 423000,China)
Abstract:Objective]To understand the type and distribution of the pathogen for hand-foot-mouth disease(HFMD)in 2009.Methods]46 stool samples from clinically diagnosed patients with HFMD were collected.Nucleic acid of three types of virus:enter virus(EV),enter virus 71(EV71)and coxasckievirus A16(CoxA16)were detected by RT-PCR and Real-Time PCR methods in samples.Results]Among the 46 cases,22 cases were EV71 positive,11 cases were EV positive and 4 cases were CoxA16 positive.The positive rate was 80.43%.Conclusio...
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