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| 加加宁口服液对高脂血症小鼠的干预效果研究 | |
| 引用本文： | 李晶洁,朱晓露,戴睿锐,杨燕,杨洋,余倩.加加宁口服液对高脂血症小鼠的干预效果研究[J].现代预防医学,2011,38(4):713-715. |
| 作者姓名： | 李晶洁 朱晓露 戴睿锐 杨燕 杨洋 余倩 |
| 作者单位： | 1. 四川大学华西公共卫生学院医学检验教研室,成都,600041 2. 昆明滇虹药业有限公司 3. 成都市疾病预防控制中心 |
| 摘 要： | 目的]研究加加宁口服液对高脂血症小鼠血脂和相关脏器的干预效果。方法]模型组昆明小鼠喂饲高脂饲料,实验组昆明小鼠喂饲高脂饲料同时以加加宁口服液(原液及3倍稀释液)灌胃,4周后检测血清TC、TG、HDL-C和LDL-C含量,测定脏器系数,观察肝脏及胰腺组织结构。结果]加加宁口服液可降低高脂血症小鼠TC、TG和LDL-C含量;恢复HDL-C含量、肝脏系数及脂肪系数;减轻高脂饮食对肝脏和胰腺的损害。结论]加加宁口服液有减轻高脂饮食对小鼠造成的脂肪代谢紊乱及脏器损害的作用。 |
| 关 键 词： | 双歧杆菌 高脂血症 脏器系数 |
STUDY ON THE INTERVENTION EFFECTS OF JIA JIA NING ORAL LIQUID ON HYPERLIPIDEMIC MICE |
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| LI Jing-jie,ZHU Xiao-lu,DAI Rui-rui,et al..STUDY ON THE INTERVENTION EFFECTS OF JIA JIA NING ORAL LIQUID ON HYPERLIPIDEMIC MICE[J].Modern Preventive Medicine,2011,38(4):713-715. | |
| Authors: | LI Jing-jie ZHU Xiao-lu DAI Rui-rui |
| Institution: | LI Jing-jie,ZHU Xiao-lu,DAI Rui-rui,et al.(West China School of Public Health,Sichuan University,Chengdu 610041,China) |
| Abstract: | Objective] To study the intervention effects of Jia Jia Ning oral liquid on lipid and related organs in hyperlipidemic mice.Methods] The hyperlipidemic model groups were fed with high fat diet.The two dosage groups were fed with high fat diet while intragastric administrated by Jia Jia Ning oral liquid(stock solution and 3 time diluent) for 4 weeks.Then we detected the content of TC,TG,HDL-C and LDL-C in blood serum and determine the organ coefficient,observed the organization structure of liver and pancr... |
| Keywords: | Bacillus bifidus Hyperlipidemia Organ coefficient |
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