氟比洛芬酯在甲状腺手术中的应用评价

目的探讨氟比洛芬酯用于甲状腺手术麻醉的有效性及安全性。方法择期甲状腺手术患者68例,麻醉方式以局麻为主,随机分为氟比洛芬酯组和对照组,每组34例。氟比洛芬酯组在对照组的基础上,在切皮前30min给予氟比洛芬酯100mg静脉注射。通过下列指标评价临床效果：（1）VAS评分;（2）局麻药和芬太尼的用量;（3）患者对术中镇痛效果总体印象评分;（4）术后24h内不良反应如恶心呕吐的发生情况。结果氟比洛芬酯组术中VAS评分较低,局麻药和芬太尼用量及加药次数显著减少,术后恶心呕吐等不良反应少（P〈0.05或P〈0.01）。结论氟比洛芬酯用于甲状腺手术可以提供满意的镇痛效果。

The Clinic Evaluation of Flurbiprofen for Patients undergoing Thyoidectomy

Objective To assess the analgesia efficacy and safety of flurbiprofen in patients undergoing thyoidectomy. Methods 68 patients, scheduled for thyoidectomy were randomly divided into flurbiprofen group and control group,34 cases in each group. All patients were received local analgesia. Flurbiprofen 100 mg in flurbiprofen group and none in control group were injected intravenously 30 minutes before operation. The clinic effects were assessed by： （1）VAS score; （2）volume and frequency of local analgesia drugs and fentanyl; （3） Patients＇ overall impression of treatment; （4）Adverse effects such as nausea and vomiting up to 24 h after operation.Results Compared with control group, VAS score, volume and frequency of analgesia drugs and fentanyl, adverse effects such as nausea and vomiting were decreased markedly （P〈0.05 or P〈0.01）. Conclusion Flurbiprofen can provide enough analgesic efficacy for patients undergoing thyoidectomy.