| 酶联免疫吸附法测定急性胰腺炎血栓素B_2、6-酮-前列腺素F_(1α)含量变化 |
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| 引用本文： | 安春生,顾统元,王家森,梁山,李乃刚. 酶联免疫吸附法测定急性胰腺炎血栓素B_2、6-酮-前列腺素F_(1α)含量变化[J]. 安徽医学, 1993, 0(4) |
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| 作者姓名： | 安春生 顾统元 王家森 梁山 李乃刚 |
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| 作者单位： | 安徽省立医院内科实验室，安徽省立医院内科实验室，安徽省立医院内科实验室，安徽省立医院外科，安徽省立医院外科 |
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| 摘 要： | 目前报道的文献大多采用放免法测定血栓素B_2(TXB_2)、6-酮-前列腺索F_(1α)(6-K-PGF_(1α)。本文应用酶联免疫吸附法(ELISA)测定了23例急性胰腺炎病人血浆TXB_2,6-K-PGF_(1α)含量,结果比正常对照组板显著地升高。全部病例经复方丹参液和(或)手术治疗,作自身对照,TXB_2、6-K-PGF_(1α)/TXB_2呈显著下降;6-K-PGF_(1α)呈极显著下降。结果提示:①急性胰腺炎与高水平TXB、6-K-PGF_(1α)有关;②复方丹参液和(或)手术抑制了TXB_2、6-K-PGF_(1α)的生成。
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TXB_1 AND 6-K-PGF_(1α) CONCENTRATION CHANGE IN ACUTE PANCREATITIS DETERMINED BY ELISA METHOD |
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| Abstract: | TXB_2 and 6-K-PGF_(1α) concentration were neasured with ELISA method in 23 cases of acute pancreatitis. They were 224.85±12.19 pg/ml and 422.28±15.05 pg/ml respectively,showing both very significantly higher concentration than that of normal control group (P<0.01). These cases whelther operated or not were all received a treatment with Radix Salviae Miltiorrhizae after treat ment,TXB_2 and 6-K-PGF_(1α)/TXB_2 ratio reduced very significantly. The results indicated: (1) Acute pancreatitis was associated with high level of both TXB_2 and 6-K-PGF_(1α), (2)Operation and administration of Radix Sahviae Miltiorrhizae might inhibite production of TXB_2 and 6-K-PGF_(1α). |
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