| 喉癌组织中核转录因子NF-kB的定量检测 |
| |
| 引用本文： | 孙余才,胡国华,朱江.喉癌组织中核转录因子NF-kB的定量检测[J].山东大学耳鼻喉眼学报,2007,21(2):141-143. |
| |
| 作者姓名： | 孙余才 胡国华 朱江 |
| |
| 作者单位： | 山东济宁医学院附属医院耳鼻喉科,山东,济宁,272100;重庆医科大学附属第一医院耳鼻喉科,重庆,400016 |
| |
| 摘 要： |
|
| 关 键 词： | 喉肿瘤 核转录因子 蛋白质印迹杂交 凝胶电泳迁移率 |
| 文章编号： | 1673-3770(2007)02-0141-03 |
| 修稿时间： | 2007年1月6日 |
A quantitative analysis of NF-kB in laryngeal carcinoma |
| |
| SUN Yu-cai,HU Guo-hua,ZHU Jiang.A quantitative analysis of NF-kB in laryngeal carcinoma[J].Journal of Otolaryngology and Ophthalmology of Shandong University,2007,21(2):141-143. |
| |
| Authors: | SUN Yu-cai HU Guo-hua ZHU Jiang |
| |
| Institution: | 1. Department of Otolaryngology, Affiliated Hospital of Jining Medical College,Jining 272100;2. Department of Otolaryngology, Affiliated First Hospital of Chongqing Medical University, Chongqing 400016 |
| |
| Abstract: | Objective: To explore the significance of the quantitative analysis of NF-kB in laryngeal carcinoma tissues. Methods: The quantitative analysis of the protein content and the DNA binding activity of NF-kB was examined by the Western blot method and electrophoretic mobility shift assay (EMSA) method in 20 cases of laryngeal carcinoma tissues and 10 cases of normal pericarcinoma tissues. Results: The protein content and the DNA binding activity of NF-kB in laryngeal carcinoma tissues were higher than those in pericarcinoma normal tissues（P<0.05）. Conclusion: The NF-kB might play an important role in the occurrence and development of laryngeal carcinoma and offers a new target of laryngeal carcinoma treatment. |
| |
| Keywords: | |
| 本文献已被 万方数据 等数据库收录！ |
| 点击此处可从《山东大学耳鼻喉眼学报》浏览原始摘要信息 |
| 点击此处可从《山东大学耳鼻喉眼学报》下载免费的PDF全文 |
