浙江省上虞市人群病毒性乙型肝炎血清流行病学调查

目的了解浙江省上虞市1～59 岁人群病毒性乙型肝炎（乙肝）感染现状，评价实施大规模乙肝疫苗（HepB）接种后的效果 。方法采用多阶段分层随机抽样的方法, 抽取664人进行了乙肝血清流行病学调查，用ELISA方法检测了乙肝病毒(HBV)表面抗原(HBsAg)、乙肝病毒表面抗体(抗-HBs)和乙肝病毒核心抗体(抗-HBc) 。结果上虞市1～59 岁人群HBsAg、抗-HBs、抗-HBc 阳性率分别是5.57%、53.46 %、32.83 %，1～14 岁人群HBsAg 阳性率为1.37%。做过创伤性美容、经常去洗浴场所（足浴店）修脚是HBsAg阳性的危险因素，拔牙、补牙、洗牙等口腔诊疗史，经常去理发店修面、修体毛或刮胡须是HBV自然感染的危险因素。与1992 年病毒性肝炎血清流行病学调查结果相比，全人群HBsAg 携带率下降47.80%(I/Isup2 /sup=7.12, IP/I＜0.01)。结论接种HepB是控制人群HBV 感染的有效措施,能明显提高抗-HBs阳性率，降低HBsAg携带率，提高人群对HBV的免疫保护能力。

Sero-epidemiological survey on prevalence of hepatitis B virus in population of Shangyu city

Objective To investigate the current status of the prevalence of hepatitis B virus(HBV) among the population aged 1 to 59 years in Shangyu city and evaluate the efficacy of large-scale vaccination of hepatitis B vaccine.MethodsA total of 664 people were selected by multi-stage stratified random sampling to conduct HBV sero-epidemiological survey.HBsAg,anti-HBs and anti-HBc were detected by using ELISA.ResultsThe positive rates of HBsAg,anti-HBs and anti-HBc were 5.57%,53.46% and 32.83% respectively among th...