| 褪黑素胶囊改善睡眠功能实验研究 |
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| 引用本文： | 张芳艳,余萍.褪黑素胶囊改善睡眠功能实验研究[J].中国实用医药,2012,7(22):29-30. |
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| 作者姓名： | 张芳艳 余萍 |
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| 作者单位： | 1. 成都医学院药学院药理教研室/重庆市食品药品检验所,610083
2. 重庆医疗器械质量检验中心 |
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| 摘 要： | 目的 研究褪黑素胶囊对小鼠睡眠改善功能.方法 通过直接睡眠实验、延长戊巴比妥钠睡眠时间实验、戊巴比妥钠阈下剂量催眠实验、巴比妥钠睡眠潜伏期实验,观察褪黑素胶囊对小鼠睡眠功能的影响.结果 褪黑素胶囊无直接睡眠作用,能显著延长戊巴比妥钠睡眠时间、协同戊巴比妥钠阈下剂量催眠作用、对巴比妥钠睡眠潜伏期无明显影响.结论 褪黑素胶囊具有改善睡眠的功效.
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| 关 键 词： | 褪黑素胶囊 改善睡眠 |
Study on sleep improvement by Melatonin capsule |
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| ZHANG Fang-yan
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YU Ping.Study on sleep improvement by Melatonin capsule[J].China Practical Medical,2012,7(22):29-30. |
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| Authors: | ZHANG Fang-yan YU Ping |
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| Institution: | .Department of Pharmacology,Pharmaceutical College of Chengdu Medical College,Chengdu 610083,China |
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| Abstract: | Objective To observe the effect of sleep improvement of Melatonin capsule.Methods The effect of Melatonin capsule were observed through experiments of sleep induced directly,prolonging sleeping time induced by pentobarbital sodium,affecting sleeping rate under the threshold hypnogenesis dosage of pentobarbital sodium,sleep delitescence induced by tobarbital sodium.Results Melatonin capsule had no direct effect on sleep,but can prolong sleeping time induced by pentobarbital sodium,and significantly increase the incidence of sleeping animals.Conclusion The Melatonin capsule can improve sleep function. |
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| Keywords: | Melatonin capsule Sleep improvement |
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