| 高架十字迷路课题中人参根和茎叶皂苷抗焦虑效果的研究 |
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| 引用本文： | 倪小虎,白洁,孙喜春,陈长好,沙雪英,于多. 高架十字迷路课题中人参根和茎叶皂苷抗焦虑效果的研究[J]. 中草药, 2001, 32(3): 238-241 |
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| 作者姓名： | 倪小虎 白洁 孙喜春 陈长好 沙雪英 于多 |
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| 作者单位： | 黑龙江商学院制药工程系，黑龙江哈尔滨 150076 |
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| 摘 要： | 目的：研究人参根和茎叶皂苷抗焦虑效果。方法：高架十字迷路法。结果：中枢兴奋药咖啡因40－80mg/kgig给药能使小鼠在开放通路中连续停留时间缩短，在封闭通路中停留时间延长。而中枢抑药定定1．5－3．0mg/kg却能明显地延长小鼠在开放通路中的停留时间，人参根和茎叶皂苷50－200mg/kgig给药后同样地使小鼠在开放通路中连续停时间延长，并且能使小鼠在开放路中往返次数增加。结论：人参根和茎叶皂苷有明显的抗焦虑效果。
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| 关 键 词： | 高架十字迷路 开放通路 封闭通路 人参根皂苷 人参茎叶皂苷 抗焦虑效果 |
| 文章编号： | 0253-2670(2001)03-0238-04 |
| 收稿时间： | 2000-07-28 |
| 修稿时间： | 2000-07-28 |
Studies on anti-anxiety effects of saponin e xtracted from root or stem and leaf of Panax ginseng in elevated crossmaze |
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| NI Xiao hu,BAI Jie,SUN Xi chun,CHEN Chang hao,SHA Xue ying and YU Duo. Studies on anti-anxiety effects of saponin e xtracted from root or stem and leaf of Panax ginseng in elevated crossmaze[J]. Chinese Traditional and Herbal Drugs, 2001, 32(3): 238-241 |
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| Authors: | NI Xiao hu BAI Jie SUN Xi chun CHEN Chang hao SHA Xue ying YU Duo |
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| Affiliation: | Department of Pharmaceutical Engineering, Heilongjiang Commercial College, Haerbin Heilongjiang 150076, China;Department of Pharmaceutical Engineering, Heilongjiang Commercial College, Haerbin Heilongjiang 150076, China;Department of Pharmaceutical Engineering, Heilongjiang Commercial College, Haerbin Heilongjiang 150076, China;Department of Pharmaceutical Engineering, Heilongjiang Commercial College, Haerbin Heilongjiang 150076, China;Department of Pharmaceutical Engineering, Heilongjiang Commercial College, Haerbin Heilongjiang 150076, China;Department of Pharmaceutical Engineering, Heilongjiang Commercial College, Haerbin Heilongjiang 150076, China |
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| Abstract: | |
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| Keywords: | elevated crossmaze open arm closed arm saponin from root of Panax ginseng C. A. Mey saponin from stem and le af of Panax ginseng C.A.Mey |
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