| COX-2及其抑制剂与结直肠肿瘤 |
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| 引用本文： | 郑燕,管杰,徐忠法. COX-2及其抑制剂与结直肠肿瘤[J]. 中华肿瘤防治杂志, 2002, 9(4): 487-490 |
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| 作者姓名： | 郑燕 管杰 徐忠法 |
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| 作者单位： | 山东省肿瘤医院,山东,济南,250117 |
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| 摘 要： | 动物实验、细胞学研究、流行病学研究和临床资料皆证明COX 2抑制剂可以在早期阶段阻止结直肠癌的发生。就COX 2理化特征、表达与调控、与结直肠癌的关系及其可能的机制予以综述
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| 关 键 词： | COX-2 抑制剂 结直肠肿瘤 综述文献 |
| 文章编号： | 1009-4571(2002)04-0487-04 |
| 修稿时间： | 2002-06-18 |
COX-2, COX-2 Inhibitor and Colorectal Tumors |
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| ZHENG Yan,GUAN Jie,XU Zhong fa.Shandong Cancer Hospital,Jinan ,China. COX-2, COX-2 Inhibitor and Colorectal Tumors[J]. Chinese Journal of Cancer Prevention and Treatment, 2002, 9(4): 487-490 |
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| Authors: | ZHENG Yan GUAN Jie XU Zhong fa.Shandong Cancer Hospital Jinan China |
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| Affiliation: | ZHENG Yan,GUAN Jie,XU Zhong fa.Shandong Cancer Hospital,Jinan 250117,China |
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| Abstract: | Animal models,cytological research,epidemiological studies and clinical trials suggest that COX 2 inhibitor may reduce the risk of colorectal tumors in early stage.Physic and chemical characters, expression and regulation of COX 2 and the relationship between COX 2 and colorectal tumors were reviewed in this article. |
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| Keywords: | COX 2 inhibitor colorectal tumor review literature |
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