早产儿足月后骨量评估及后期追踪

目的：对早产儿校正胎龄足月后骨矿密度（BMD）、血钙磷、血碱性磷酸酶（ALP）检查及后期追踪探讨早产儿骨骼发育。方法：选择≤31周早产儿在校正胎龄37周后行双能X线吸收测定术（DEXA）测定BMD，测定血钙、血磷、ALP，与足月儿对照，并后期追踪。结果：BMD：早产儿30例，腰椎I。1～。（0．10±0．04）g／cm。，左、右前臂均为（0．11±0．04）g／cm2；足月儿20例，腰椎L1-4（0．18±0．09）g／cm2，左、右前臂均为（O．23±0．03）g／cm2，两组比较差异有统计学意义（P〈0．05）；血ALP值两组比较差异具有统计学意义（P〈0．05）；血钙磷值比较差异无统计学意义（P〉0．05）；早产儿追踪至6个月，身高头围均达到同龄儿标准。结论：本组BMD检查可发现早产儿足月后骨量仍相对不足，需重视矿物质的补充，但远期的头围身高发育均不受影响。

Bone mass assessment and the later follow-up of premature infants after fullterm

Objective： To investigate the bone development of the premature infants through the bone mineral density（BMD）, serum calcium phosphorus, and alkaline phosphatase（ALP） measurement of the premature infants after the full-term of the corrected gestational age（GA）. Methods： Pre term whose GA was less than or equal to 31w were selected, and their BMD, calcium phosphorus and ALP were determined by by dual-energy X-ray absorptiometry technique after 37 of their corrected GA. The results were compared with those of the term infants, and tracked. Results： BMD of 30 preterm infants showed： lumbar vertebra（0.10±0.04） g/cm2 , forearm（0. 11±0.04） g/cm2 ; while BMD of 20 fullterm infants showed, lumbar vertebra（0.18±0.09） g/era2, forearm（0.23±0.03） g/Cm2. There was statistical difference between the two groups（P〈0.05） ; there was statistical difference of the serum ALP between both groups（P〈0.05） ; but there was no significant difference of the calcium phosphorus value between both groups（P〉0.05）. The tracking results showed that after six months＇ growth, the body height, head circumference of the premature in rants could reach the same standard of the term infants of the same age. Conclusion： The detection results shows that BMD of the preterm infants after fullterm is still relatively insufficient, importance should be attached to the minerals supplement, but the long-term head circumference and height growth are unafected.