缬沙坦联合硝苯地平缓释片治疗原发性高血压的临床疗效观察

目的：探讨缬沙坦联合硝苯地平缓释片治疗原发性高血压的临床疗效。方法：选择我院内科门诊治疗的86例原发性高血压患者，随机分为缬沙坦联合硝苯地平缓释片治疗组（A组，n=43）和单用缬沙坦对照组（B组，n=43）。对两组患者治疗4周后的有效性和安全性进行比较。结果：两组血压均有下降，A组下降明显，治疗总有效率95．3％，B组总有效率76．7％，两组比较差异有统计学意义（P〈0．05）。结论：缬沙坦联合硝苯地平缓释片治疗原发性高血压降压有效率优于单用缬沙坦。

Observation of the clinical curative effect of valsartan combined with extended release nifedipine tablets on trea- ting primary hypertension

Objective： To investigate the clinical curative effect of valsartan combined with extended release nifedipine tablets on the treatment of primary hypertension. Methods： 86 cases of primary hypertension patients treated in the Clinic of Internal Medicine were randomized into the valsartan combined with extended release nifedipine tablets therapy group（Group A, n=43） and the control group treated with valsartan only（Group B,n=43）. 4 weeks after the treatment, the efficacy and safety of both groups were compared. Results： Blood pressure of patients in both groups had dropped, but group A decreased more significantly with the total effective rate of 95.3 % ; while the total effective rate of B group was 76. 70//00. There was of statistical difference between the two groups（P〈0.05）. Conclusion： The antihypertensive effect of valsartan combined with extended release nifedipine tablets on treating primary hypertension is superior to that of valsartan alone.