Congenital Langerhans cell histiocytosis with skin and lung involvement: Spontaneous regression |
| |
Authors: | Varun Aggarwal Anju Seth Manjula Jain Sriram Krishnamurthy Varkha Chandra Satinder Aneja |
| |
Affiliation: | 1.Department of Pediatrics,Lady Hardinge Medical College and Kalawati Saran Children’s Hospital,New Delhi,India;2.Department of Pathology,Lady Hardinge Medical College and Kalawati Saran Children’s Hospital,New Delhi,India |
| |
Abstract: | Congenital self-healing Langerhans cell histiocytosis (CSHLCH) is a rare type of Langerhans Cell Histiocytosis, presenting at birth or during the neonatal period with eruption of multiple, discrete red-brown papules or nodules that undergo spontaneous regression. Systemic signs are generally absent. We describe a 4-month-old infant presenting with reddish brown nodular cutaneous lesions since birth with a past history suggestive of pulmonary involvement. Skin biopsy showed a dermal infiltrate of pleomorphic histiocytes; which were CD1a and S-100 positive, consistent with the diagnosis of CSHLCH. Both pulmonary and cutaneous lesions showed spontaneous resolution. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|