| 盐酸氨溴索辅助治疗慢性支气管炎急性加重期的临床效果 |
| |
| 引用本文： | 曾桂珍,张俊.盐酸氨溴索辅助治疗慢性支气管炎急性加重期的临床效果[J].中国当代医药,2014,21(29):77-79. |
| |
| 作者姓名： | 曾桂珍 张俊 |
| |
| 作者单位： | 江西省上栗县人民医院内一科,江西上栗,337009 |
| |
| 摘 要： | 目的 探讨盐酸氨溴索辅助治疗慢性支气管炎急性加重期的临床效果.方法 选取600例慢性支气管炎急性加重期患者,并采用信封法随机分为两组,对照组患者给予解痉、平喘、吸氧、抗感染、糖皮质激素静脉滴注等对症支持治疗,观察组患者在对照组的基础上加用盐酸氨溴索注射液静脉滴注治疗.观察两组的治疗效果.结果 观察组患者的治疗总有效率为96.67％,对照组为80.00％,观察组的总有效率明显高于对照组（P＜0.05）;治疗后观察组患者的SaO2明显高于对照组（P＜0.05）;治疗后观察组患者的咳嗽、咳痰、喘息症状评分分别为（0.8±0.2）、（0.6±0.5）、（0.7±0.2）分,明显低于对照组的（1.4±0.5）、（1.5±0.7）、（1.5±0.8）分（P＜0.05）;观察组20例（6.67％）发生不良反应,对照组10例（3.33％）发生不良反应,两组比较差异无统计学意义（P＞0.05）.结论 盐酸氨溴索辅助治疗慢性支气管炎急性加重期可明显提高效果,安全性高.
|
| 关 键 词： | 盐酸氨溴索 慢性支气管炎急性加重期 临床疗效 |
Clinical effect of ambroxol hydrochloride auxiliary treatment of acute exacerbation of chronic bronchitis |
| |
| Authors: | ZENG Gui-zhen ZHANG Jun |
| |
| Institution: | (One Medicine Department,People＇s Hospital of Shangli County in Jiangxi Province,Shangli 337009,China ) |
| |
| Abstract: | Objective To explore the clinical effect of ambroxol hydroehloride auxiliary treatment of acute exacerbation of chronic bronchitis. Methods 600 patients with acute exacerbation of chronic bronchitis were selected and randomly divided into two groups by envelope method,the control group patients were given spasmolysis,smooth wheezing,oxygen, anti-infection and glucoeorticoid intravenous drip support therapy,the observation group patients were given ambroxol hydroehloride injection intravenous drip treatment on the basis of control group,the treatment effect of two groups were observed. Results The total effective rate of observation group was 96.67%,the control group was 80.00%,the total effective rate of observation group was significantly higher than that of control group （P〈0.05）.The SaO2 of the observation group after treatment was significantly higher than that of the control group （P〈0.05）.The cough,sputum,wheezing symptom scores in observation group after treatment of （0.8±0.2）,（0.6±0.5）,（0.7±0.2） scores respectively,were significantly lower than the （1.4±0.5）,（1.5±0.7）,（1.5±0.8） scores respectively of the control group （P〈0.05）.The observation group had 20 cases （6.67%） occurred adverse reactions,the control group had 10 （3.33%） occurred adverse reactions,there was no statistically significant difference between the two groups （P〉0.05）. Conclusion Ambroxol hydrochloride in treatment of acute exacerbation of chronic bronchitis can significantly improve the efficacy,and it is safety. |
| |
| Keywords: | Ambroxol hydrochloride Acute exacerbation of chronic bronchitis Clinical efficacy |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
