外科手术抗菌药物预防性应用调查分析

目的：探讨外科手术抗菌药物预防性应用存在的问题。方法：对外科336例清洁、清洁-污染手术抗菌药物预防性应用进行前瞻性调查分析。结果：336例手术患者中，抗菌药物使用占99．10％；清洁手术、清洁-污染手术一、二和三联抗菌药物使用分别占27．39％、70．78％、6．72％、93．30％；术前、术后用抗菌药物分别占13．69％、8514％：术后预防性用药时间〉3天占86．78％，其中用药时间最长18天；抗菌药物使用最多为头孢菌素类。结论：外科手术抗菌药物预防性应用不够规范．用药指征掌握不够准确，药物联用、用药时机、药物选择不够合理，用药时间持续较长，应进一步重视抗菌药物的规范、合理使用。

Survey on operative prophylactic antibiotics application

Objective ：To understand the existing problems in operative prophylactic antibiotics application. Methods ：The prospective survey on operative prophylactic antibiotics application in 336 cases of clean operation,clean-contaminated operation was performed. Results：Among 336 surgical patients, antibiotics application accounted for 99.10% ,single, two-drug and three--drug usage in clean operation ,clean-contaminated operations accounted for 27.36%. 70.78%, 6.72% ,93.30% respectively. Preoperative and postoperative antibiotics usage accounted for 13.69% and 85.4% respectively,postoperative prophylactic antibiotics application 〉3 d accounted for 86.78%, the longest usage duration lasted 18 d.Cephalosporin was most commonly used. Conclusion：Operative prophylactic antibiotics application is not standardized enough, mastering indication of antibiotics usage is not accurate enough, drug combination, use time and drug selection are unreasonable and drug usage time sustains longer. The rational and standardized usage of antibiotics should be further strengthened.