主动脉瓣钙化与冠心病的相关性研究

目的 探讨珠海地区汉族人群主动脉瓣钙化（AVC）与冠心病的相关性.方法 回顾性研究心内科住院患者1140例.所有患者均同期行超声心动图和冠状动脉造影检查,分析AVC与冠心病的相关性.结果 冠心病组中检出AVC的比率明显高于非冠心病组（32.3％比13.8％,P＜0.01）.冠心病组AVC患者冠脉受累严重程度高于无AVC患者.多因素分析显示,AVC、年龄、性别、高脂血症和糖尿病为全组冠心病的独立预测因子（P＜0.05）.结论 AVC与冠心病之间存在显著的相关性,对预测冠心病有一定参考价值.

Relationship between aortic valve calcification and coronary artery disease

Objective To determine the relationship between aortic valve calcification （AVC） and coronary artery disease （CAD） among part population of Han Nationality of ZhuHai.Methods 1140 subjects who underwent both transthoracic echocardiography（TTE） and coronary arteriography（CAG） were enrolled,and the relationship between aortic valve calcification （AVC） and CAD was explored.Results The prevalence of AVC was significantly higher in CAD group than in normal coronary group （32.3% vs 13.8%,P〈0.01）,multiple logistic regression analysis identified age（P〈0.01）,male gender（P〈0.01）,diabetes mellitus （P〈0.01）,hyperlipemia（P〈0.01） and AVC （P〈0.01） as independent predictor for the positive prevalence of coronary arteriography.Conclusion There was a significant association between the presence of AVC and CAD.AVC have a certain reference value for predicting CAD.