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| 植物提取物的质量控制 | |
| 引用本文： | 邵云东,高文远,刘丹,贾伟,段宏泉,张铁军. 植物提取物的质量控制[J]. 中国中药杂志, 2003, 28(10): 899-903 |
| 作者姓名： | 邵云东 高文远 刘丹 贾伟 段宏泉 张铁军 |
| 作者单位： | 1. 天津大学,药物科学与技术学院,天津,300072 2. 南京工业大学制药与生命科学学院,江苏,南京,210009 3. 上海交通大学,药学院,上海,200030 4. 天津药物研究院,天津,300192 |
| 摘 要： | 概述了植物提取物行业的国内外现状 ,并比较和分析了美国市场上畅销的前 20位植物提取物的产品质量控制现状。对6个提取物品种的分析表明 ,造成植物提取物质量水平差异的主要原因有两个 ,即提取物原料使用的品种差异和不同公司提取分离的工艺差异。目前我国植物提取物的质量控制水平与国外大公司相比还不够高 ,应以色谱技术及色谱指纹图谱技术为手段 ,快速提升我国植物提取物的质量控制水平。 |
| 关 键 词： | 植物提取物 质量控制 指纹图谱 |
| 文章编号： | 1001-5302(2003)10-0899-05 |
| 收稿时间： | 2003-07-07 |
| 修稿时间： | 2003-07-07 |
Quality Control of Plant Extract |
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| SHAO Yun-dong ;GAO Wen-yuan ;LIU Dan ;JIA Wei ;DUAN Hong-Quan ;ZHANG Tie-jun. Quality Control of Plant Extract[J]. China Journal of Chinese Materia Medica, 2003, 28(10): 899-903 | |
| Authors: | SHAO Yun-dong GAO Wen-yuan LIU Dan JIA Wei DUAN Hong-Quan ZHANG Tie-jun |
| Affiliation: | The College of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China. |
| Abstract: | The current situation of plant extract in domestic and international market was analyzed in the paper. The quality control of 20 plant extracts which have reasonably good sales in USA market was compared and analyzed. The analysis of the quality control of six plant extracts indicated that there were two main reasons leading to the varied quality specifications among different suppliers. One reason was that the plant species utilized by different companies were different. The other reason was that the extraction processes were different among different production plants. Comparing with the significant international suppliers of plant extracts, the product quality of Chinese companies were not satisfactory. It was suggested that chromatography and chromatographic fingerprint techniques should be applied to improve the quality control standard of plant extract in our country. |
| Keywords: | plant extract quality control chromatography fingerprint |
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