高压氧治疗颅脑损伤后抑郁的疗效分析

目的探讨高压氧治疗对颅脑损伤后抑郁患者日常生活活动能力和抑郁心理的影响。方法将76例颅脑损伤后抑郁患者随机分成高压氧组和对照组,每组38例,两组患者均采取常规药物治疗,并适当给予功能康复指导。高压氧组在病情稳定后尽早进行高压氧治疗。在患者入选时、病程3个月时分别进行Barthel指数和HAMD评定。结果与对照组比较,高压氧组患者Barthel指数得分在疗程3月时显著提高(P<0.01),HAMD得分在疗程3个月时则明显降低(P<0.01)。结论高压氧综合治疗能够有效改善颅脑损伤后抑郁患者的日常生活活动能力,减轻抑郁心理。

Analysis of Therapeutic Effect of Hyperbaric Oxygen on Depression after Craniocerebral Injury

Objective To discuss the effect of hyperbaric oxygen(HBO) therapy on the daily living activity and depression after craniocerebral injury.Methods All the 76 patients with depression after craniocerebral injury were divided into two groups at random,i.e.HBO group(n=38) and control group(n=38).Both the two groups were treated with routine medication plus guidance of functional rehabilitation.The HBO group was additionally treated with HBO therapy as soon as the disease condition became stable.Barthel index and Hamilton depression rating scale(HAMD) were measured respectively before therapy and after three months' therapy.Results Barthel index of the HBO group increased significantly after three months' therapy when compared with that of the control group,whereas its HAMD decreased obviously(P<0.01).Conclusion Combined HBO therapy can improve the patients' daily living activity and depression after they suffer from craniocerebral injury.