| 膳食脂肪与肺癌的可能机制研究进展 |
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| 引用本文： | 王俊芳,黄承钰,李思汉. 膳食脂肪与肺癌的可能机制研究进展[J]. 卫生研究, 2004, 33(3): 383-385 |
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| 作者姓名： | 王俊芳 黄承钰 李思汉 |
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| 作者单位： | 1. 四川大学公共卫生学院,成都,610041
2. 山西医科大学营养与食品卫生学教研室 |
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| 摘 要： | 大量的流行病学研究表明膳食脂肪与肺癌的关系非常密切 ,但尚缺乏有关机制方面的研究。本文综述了高脂膳食引发肺癌的可能机制 ,包括脂肪酸比例失调、胰岛素抵抗、脂质过氧化、内分泌机制、细胞因子分泌异常、细胞膜流动性改变等 ,旨在为以后的病因学研究提供参考。
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| 关 键 词： | 膳食脂肪 肺癌 胰岛素抵抗 细胞因子 |
| 文章编号： | 1000-8020(2004)03-0383-03 |
| 修稿时间： | 2003-11-03 |
Research progress on dietary fat and the development of lung cancer |
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| Wang Junfang,Huang Chengyu,Li Sihan Huaxi School of Public Health,Sichuan University,Chengdu ,China. Research progress on dietary fat and the development of lung cancer[J]. Journal of hygiene research, 2004, 33(3): 383-385 |
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| Authors: | Wang Junfang Huang Chengyu Li Sihan Huaxi School of Public Health Sichuan University Chengdu China |
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| Affiliation: | Huaxi School of Public Health, Sichuan University, Chengdu 610041, China. |
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| Abstract: | The epidemiological studies showed close relations between dietary fat and lung cancer, but large gaps still exist in understanding.There were no mechanical indications to confirm some conclusions. In this paper, the possible mechanisms including imbalance of fatty acid ratios, insulin resistance, lipids peroxidation, endocrine mechanism, cytokine abnormality and membrane fluidity changes were reviewed. |
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| Keywords: | dietary fat lung cancer insulin resistance cytokine |
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