| 依前列醇多样的信号选择 |
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| 引用本文： | Wise H. 依前列醇多样的信号选择[J]. Acta pharmacologica Sinica, 2003, 24(7): 625-630,724 |
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| 作者姓名： | Wise H |
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| 作者单位： | DepartmentofPharmacology,FacultyofMedicine,TheChineseUniversityofHongKong,Shatin,NewTerritories,HongKongSAR,China |
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| 摘 要： | The fate of a cell following stimulation by the prostanoid prostacyclin is cell specific, depending not only on the ability of prostacyclin to activate the cell surface prostacyclin (IP) receptor and regulate its coupling to various G proteins, but also on its ability to act intracellularly via the nuclear peroxisome proliferator-activated receptor family (PPAR). This review will highlight the different signalling options available to prostacyclin, and discuss the consequences for cell responses.
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| 关 键 词： | 依前列醇 信号选择 环前列腺素 核过氧化酶 环氧合酶 细胞因子 |
Multiple signalling options for prostacyclin |
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| Wise Helen. Multiple signalling options for prostacyclin[J]. Acta pharmacologica Sinica, 2003, 24(7): 625-630,724 |
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| Authors: | Wise Helen |
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| Affiliation: | Department of Pharmacology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China. helenwise@cuhk.edu.hk |
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| Abstract: | The fate of a cell following stimulation by the prostanoid prostacyclin is cell specific, depending not only on the ability of prostacyclin to activate the cell surface prostacyclin(IP) receptor and regulate its coupling to various G proteins, but also on its ability to act intracellularly via the nuclear peroxisome proliferator-activated receptor family(PPAR). This review will highlight the different signalling options available to prostacyclin, and discuss the consequences for cell responses. |
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| Keywords: | epoprostenol IP receptors peroxisome proliferator-activated receptors receptor switching |
| 本文献已被 CNKI 维普 PubMed 等数据库收录！ |
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