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L_9(3~4)正交试验评价碘伏及增效剂对HBsAg灭活效果
引用本文:李慧,丁丽,方煜平. L_9(3~4)正交试验评价碘伏及增效剂对HBsAg灭活效果[J]. 现代医学, 1993, 0(1)
作者姓名:李慧  丁丽  方煜平
作者单位:南京铁道医学院流行病学教研室 210009
摘    要:为能有效地提高目前常用的消毒剂碘伏对乙型肝炎病毒的灭活能力,我们在一定条件下于碘伏液中加入一定量的表面活性剂十六烷基三甲基溴化铵,结果显示后者对碘伏消毒效果有明显增效作用,能提高消毒效率约3.6倍。试验采用正交设计,还同时考虑了消毒时间,温度两个因素。结果显示时间、温度因素影响不明显。

关 键 词:消毒剂  乙型肝炎表面抗原  乙型肝炎病毒

Evaluation of Iodophor and Its Synergist in Inactivating HBsAg by L_9(3~4) Orthogonal Design Test
Li Hui,Teaching Group of Epidemiology,Nanjing Railway Medical College. Evaluation of Iodophor and Its Synergist in Inactivating HBsAg by L_9(3~4) Orthogonal Design Test[J]. Modern Medical JOurnal, 1993, 0(1)
Authors:Li Hui  Teaching Group of Epidemiology  Nanjing Railway Medical College
Affiliation:Li Hui,Teaching Group of Epidemiology,Nanjing Railway Medical College,210009
Abstract:Our experiment showed that cetyitrimethylammonium bromide had the esynergetic effect to iodophor in inactivating HBsAg. The solution containing 25ppm effective iodine within 10-30 minutes of contact time could inactivate about 23.07% of HBsAgo However, the solution containing 25ppm effective iodine and 0.5% cetyltrimethylammonium bromide could inactivate 83.56% of HBsAg within the same contact time.
Keywords:disinfectants   hepatitis B surface antigens   hepatitis B virus
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