A role of genomic copy number variation in the complex behavioral phenotype of alcohol dependence: a commentary |
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| Authors: | Alexander E Urban |
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| Affiliation: | Department of Psychiatry and Behavioral Sciences, Department of Genetics (AEU), Stanford University School of Medicine, Palo Alto, California. |
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| Abstract: | In their paper "Copy number variations in 6q14.1 and 5q13.2 are associated with alcohol dependence" Lin and colleagues report on the association between alcohol dependence and 2 duplication CNVs in the genome sequence, one containing 8 genes within its boundaries and another that contains no genes. In this commentary, I point out some of the opportunities and challenges that arise from such a finding. |
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| Keywords: | Complex Disorder Genome Variation Segmental Duplications Regulatory Regions Genome Technology |
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