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淋巴显像技术在口腔鳞癌哨位淋巴结活检中的应用
引用本文:张胜,陈伟良,李劲松,刘生,卢献平. 淋巴显像技术在口腔鳞癌哨位淋巴结活检中的应用[J]. 中国口腔颌面外科杂志, 2004, 2(3): 140-144
作者姓名:张胜  陈伟良  李劲松  刘生  卢献平
作者单位:1. 广东东莞市人民医院,口腔颌面外科,广东,东莞,523018
2. 中山大学附属第二医院,口腔颌面外科,广东,广州,510120
3. 中山大学附属第二医院核医学科,广东,广州,510120
基金项目:广东省医学科研基金(A2004196)中山医科大学孙逸仙纪念医院科研基金(F000099132)
摘    要:目的:评价淋巴显像技术在口腔鳞癌哨位淋巴结活检中的价值。方法:应用颈淋巴显像技术结合蓝染法及SPECT/CT同机融合技术,对21例临床NO(cNO)口腔鳞癌患者的哨位淋巴结(sentinel lymph node,SLN)进行研究。结果:全组患者SLN检出率为100%,21例中有7例SLN活检阳性,颈清术后标本同样证实有颈淋巴结转移,无假阴性结果,SLN活检对全组病例颈淋巴结转移状况预测的准确性为100%。结论:颈淋巴显像技术结合蓝染法及SPECT/CT同机融合技术能有效地对口腔鳞癌SLN进行定位,从而准确预测颈淋巴结转移状况。

关 键 词:淋巴闪烁摄影术    鳞状细胞  口腔癌  哨位淋巴结  淋巴转移
文章编号:1672-3244(2004)03-0140-05
修稿时间:2003-10-27

Lymphoscintigraphy in sentinel lymph node biopsy of oral squamous cell carcinoma
ZHANG Sheng,CHENWei-liang,LI Jin-song,LIU Sheng,LU Xian-ping.. Lymphoscintigraphy in sentinel lymph node biopsy of oral squamous cell carcinoma[J]. China Journal of Oral and Maxillofacial Surgery, 2004, 2(3): 140-144
Authors:ZHANG Sheng  CHENWei-liang  LI Jin-song  LIU Sheng  LU Xian-ping.
Abstract:PURPOSE: To assess the clinical value of lymphoscintigraphy in detecting sentinel lymph node (SLN) in oral squamous cell carcinoma. METHODS:Sentinel lymph node of twenty-one patients with oral squamous cell carcinoma without clinical lymph metastasis (cN0) were investigated using lymphoscintigraphy combined with methylene blue or a hybrid SPECT/CT system. RESULTS: SLN was successfully identified in all of the 21 patients, 7 (33.3%) cases were found lymph node metastasis positive pathologically . The samples of elective neck dissection also contained tumor cells in these 7 patients . There were no false negatives and the accuracy rate of SLN was 100%. CONCLUSIONS: The detection of SLN using lymphoscintigraphy combined with methylene blue or a hybrid SPECT/CT system could accurately identify the SLN and predict cervical lymph node metastasis in oral squamous cell carcinoma.
Keywords:Lymphoscintigraphy  Squamous cell carcinoma  Oral cancer  Sentinel lymph node  Lymphatic metastasis
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