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Amacrine and horizontal cell dysfunction in adult ceroid-lipofuscinosis (Kufs disease) and anatomical correlates in the ovine model |
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| Authors: | Donald Armstrong Marcus Benedetto Donald Samuelson |
| Institution: | (1) University of Florida College of Medicine, 32610 Gainesville, FL, USA;(2) University of Florida College of Veterinary Medicine, 32610 Gainesville, FL, USA;(3) Department of Ophthalmology, University of Florida College of Medicine, Box J-284, 32610 JHMHC, Gainesville, FL, USA |
| Abstract: | Psychophysical examination of the visual performance of a patient with Kufs disease suggests abnormal functioning of the amacrine and horizontal cell systems of lateral inhibition. The sheep model offers insight into early patho-physiology of these cell types. |
| Keywords: | ceroid-lipofuscinosis amacrine cell horizontal cell |
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