Transient increase of NMDA-binding sites in human hippocampus during development |
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Authors: | A Represa E Tremblay Y Ben-Ari |
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Affiliation: | Inserm U29, H?pital de Port Royal, Paris, France. |
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Abstract: | In the human hippocampus, the density of glutamate and N-methyl-D-aspartate (NMDA) binding sites follows during development a bell-shaped curve with a peak at 23-27 fetal weeks. We suggest that there is a transient increased density of NMDA binding sites during a restricted period of hippocampal development; this may play an important role in developmental plasticity. |
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