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2型糖尿病合并急性冠状动脉综合征患者血运重建预后的评价
引用本文:王燕燕,郭华,钟勇,王坚.2型糖尿病合并急性冠状动脉综合征患者血运重建预后的评价[J].中华老年心脑血管病杂志,2009,11(4).
作者姓名:王燕燕  郭华  钟勇  王坚
作者单位:南京军区总医院,南京,210002
摘    要:目的探讨2型糖尿病合并急性冠状动脉综合征(acute coronary syndrome,ACS)患者经血运重建治疗对远期预后的影响。方法选择ACS患者424例,根据是否合并糖尿病分为糖尿病组(120例)和无糖尿病组(304例)。分析两组患者冠状动脉造影、冠状动脉支架置入术的临床资料以及两组患者术后2年的随访资料。结果糖尿病组患者冠状动脉3支、多支、闭塞性病变比率明显高于无糖尿病组(P<0.05):糖尿病组患者不完全血运重建的比率高于无糖尿病组,完全血运重建的比率低于无糖尿病组(P<0.05):糖尿病组惠青生活质量改善率低于无糖尿病组,重大心血管事件的发生率高于无糖尿病组(P<0.05)。结论糖尿病合并ACS患者冠状动脉以3支、多支、重度、闭塞病变为主的特点,且其远期预后较差。

关 键 词:糖尿病  2型  冠状动脉疾病  冠状血管造影术  预后  生活质量  心肌血管重建术

Assessment of prognosis of coronary artery revascularization in acute coronary syndrome patient with type 2 diabetes mellitus
Abstract:Objective To analyse the effect of DM on the long term prognosis of the acute coronary syndrome patient who had coronary artery revascularization. Methods One hundred-twenty acute coronary syndrome patients with type 2 diabetes(DM group) and 304 acute coronary syndrome patients without diabetes(non-DM group) undergoing coronary angiography and percutaneous coronary intervention during hospitalization were studied. Results The rates of triple-vessel,multiple branches and obstruction lesions were higher in patients of DM group than in non-DM group. The rate of incomplete coronary artery revascularization was higher and the rate of complcte coronary artery revascularizaticn was lower in patients of DM group than in patients of non-DM group (P<0.05). DM group had more major adverse cardiac events and worse quality of life than non-DM group had (P<0.05). Conclusion The acute coronary syndrome patients with diabetes mellitus have severer coronary lesions and worse outcomes than the patients without DM.
Keywords:diabetes mellitus  type 2  coronary disease  coronary angiography  prognosis  quality of life  myocardial revascularization
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