| 愈消通脉散对糖尿病大鼠血浆和脑组织内皮素 降钙素基因相关肽水平的影响 |
| |
| 引用本文： | 宋福印,陈孝银. 愈消通脉散对糖尿病大鼠血浆和脑组织内皮素 降钙素基因相关肽水平的影响[J]. 辽宁中医药大学学报, 2010, 0(2) |
| |
| 作者姓名： | 宋福印 陈孝银 |
| |
| 作者单位： | 北京同仁堂中医医院;暨南大学医学院; |
| |
| 摘 要： | 目的:通过检测愈消通脉散对糖尿病大鼠血浆和脑组织内皮素、降钙素基因相关肽水平的影响,探讨上述物质在糖尿病性脑病中的作用机理及愈消通脉散对其的调控作用。方法:采用放射免疫法检测糖尿病大鼠血浆和脑组织内皮素(ET)和降钙素基因相关肽(CGRP)水平的变化。结果:模型组大鼠血浆和脑组织内皮素-1水平与正常对照组比较显著升高,降钙素基因相关肽水平与正常组比较显著降低;中药组大鼠内皮素、降钙素基因相关肽水平与对照组比较均无显著性差异。结论:愈消通脉散防治糖尿病性脑病的机理与其调节血浆和脑组织的内皮素-1和降钙素基因相关肽水平有关。
|
| 关 键 词： | 愈消通脉散 糖尿病 ET-1 CGRP |
Effects of Yuxiao Tongmai San on the Encephalic and Plasma ET CGRP of Rats in Diabetes Mellitus |
| |
| SONG Fu-Yin,CHEN Xiao-Yin. Effects of Yuxiao Tongmai San on the Encephalic and Plasma ET CGRP of Rats in Diabetes Mellitus[J]. Journal of Liaoning University of Traditional Chinese Medicine, 2010, 0(2) |
| |
| Authors: | SONG Fu-Yin CHEN Xiao-Yin |
| |
| Affiliation: | 1.Beijing Tongrentang TCM Hospital/a>;Beijing 100051/a>;China/a>;2.Medical College of Ji'nan University/a>;Guangzhou 510632/a>;Guangdong/a>;China |
| |
| Abstract: | Objective:To investigate the effects of Yuxiao Tongmai San on the encephalic and plasma ET,CGRP of rats in diabetes mellitus and its mechanism. Method:Radio-immunology method is used to detect encephalic and plasma ET,CGRP in rat of diabetes mellitus. Result:The plasma ET-1 in the rats of model group is higher than the control group,while the encephalic CGRP is on the contrary; the ET-1 and CGRP in Yuxiao Tongmai San treatment group is no obvious difference than the control group. Conclusion:The mechanism f... |
| |
| Keywords: | Yuxiao Tongmai San diabetes mellitus ET-1 CGRP |
| 本文献已被 CNKI 等数据库收录！ |
