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嗜碱粒细胞组胺释放试验检测抗高亲和力IgE抗体及其受体
引用本文:刘荣卿,孙仁山. 嗜碱粒细胞组胺释放试验检测抗高亲和力IgE抗体及其受体[J]. 重庆医学, 2001, 30(1): 27-28
作者姓名:刘荣卿  孙仁山
作者单位:第三军医大学西南医院皮肤科
摘    要:目的 探讨慢性荨麻疹的发生机制。方法 用嗜碱粒细胞组胺释放试验,检测慢性特发性荨麻疹患者的血清组胺释放活性。结果 32例中,有15例(46.9%)患者血清组胺释放活性增高,提示FcεR1抗IgE自身抗体的存在。结论 部分慢性荨麻疹的发生与自身免疫机制有关。

关 键 词:慢性特发性荨麻疹 嗜碱粒细胞组胺释放试验 自身抗体 IgE抗体 受体
文章编号:1000-7911(2001)01-0027-02

Significance of basophil histamine release assays in chronic urticaria
LIU Rong-qing,Sun Ren-shan. Significance of basophil histamine release assays in chronic urticaria[J]. Chongqing Medical Journal, 2001, 30(1): 27-28
Authors:LIU Rong-qing  Sun Ren-shan
Abstract:Objective To Investigate the pathogenesis of chronic idiopathic urticaria.Methods Basophil histamine release assay was utilized.Result 15 of 32 cases(46.9%)had increased serum histamine releasing activities. This implied that anti-FcεR1 and anti-IgE autoantibodies existed in the sera of some patients with chronic idiopathic urticaria.Conclusion It suggested that autoimmunity might take part in the occurrence of some patients with chronic idiopathic urticaria.
Keywords:chronic idiopathic urticaria  autoantibody  basophil histamine release assay
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