Multicenter study for the evaluation of a dedicated biopsy device for MR-guided vacuum biopsy of the breast |
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Authors: | Perlet C Heinig A Prat X Casselman J Baath L Sittek H Stets C Lamarque J Anderson I Schneider P Taourel P Reiser M Heywang-Köbrunner S H |
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Affiliation: | Institute of Clinical Radiology, Ludwig Maximilians University, Klinikum Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany. |
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Abstract: | The purpose of this multicenter study was to determine the accuracy and clinical value of a dedicated breast biopsy system which allows for MR-guided vacuum biopsy (VB) of contrast-enhancing lesions. In five European centers, MR-guided 11-gauge VB was performed on 341 lesions. In 7 cases VB was unsuccessful. This was immediately realized on postinterventional images or direct follow-up combined with histopathology-imaging correlation; thus, a false-negative diagnosis was avoided. Histology of 334 successful biopsies yielded 84 (25%) malignancies, 17 (5%) atypical ductal hyperplasias, and 233 (70%) benign entities. Verification of malignant or borderline lesions included reexcision of the biopsy cavity. Benign histologic biopsy results were verified by retrospective correlation with the pre- and postinterventional MRI and by subsequent follow-up. Our results indicate that MR-guided VB, in combination with the dedicated biopsy coil, offers the possibility to accurately diagnose even very small lesions that can only be visualized or localized by MRI. |
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Keywords: | Breast MR imaging Biopsy Intervention |
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