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Oral mucosal involvement and petechial lesions: a SDRIFE case with unusual findings
Authors:Ayse Serap Karadag  Emin Ozlu  Necmettin Akdeniz  Tugba Kevser Uzuncakmak  Zafer Turkoglu  Seyma Ozkanli
Institution:1. Department of Dermatology, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey, karadagaserap@gmail.com;3. Department of Dermatology, Faculty of Medicine, Goztepe Research and Training Hospital, Istanbul Medeniyet University, Istanbul, Turkey,;4. Department of Dermatology, Faculty of Medicine, Goztepe Research and Training Hospital, Istanbul Medeniyet University, Istanbul, Turkey,;5. Department of Dermatology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey,;6. Department of Dermatology Goztepe Research and Training Hospital, Istanbul Medeniyet University, Istanbul, Turkey,;7. Department of Dermatology, Goztepe Training Hospital, Medeniyet University, Istanbul, Turkey, and
Abstract:Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) is a type IV hypersensitivity reaction characterized by a symmetrical erythematous rash in the gluteal and intertriginous areas. SDRIFE was previously considered to be the same presentation as Baboon Syndrome, however, has been suggested to be a different entity in the recent publications. The lesions are generally maculopapular and there is no mucosal involvement. To date, no case with petechial findings and mucosal involvement has been reported in the literature. The present study reports a SDRIFE case with a symmetrical erythematous petechial rash and oral mucosal involvement after taking oral amoxicillin.
Keywords:Drug eruption  drug toxicity  SDRIFE
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