Cervical length,risk factors,and delivery outcomes among women with spontaneous preterm birth |
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| Authors: | Rupsa C. Boelig Kelly M. Orzechowski Vincenzo Berghella |
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| Affiliation: | 1. Division of Maternal Fetal Medicine, Department of Obstetrics &2. Gynecology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA and rupsa.c@gmail.com;4. Department of Maternal Fetal Medicine, Virginia Hospital Center, Arlington, VA, USA;5. Gynecology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA and |
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| Abstract: | Objectives: To evaluate differences in risk factors and delivery outcomes among women with spontaneous preterm birth (sPTB) with short (≤25?mm) versus normal (>25?mm) cervical length (CL).Methods: Secondary analysis of a prospective cohort study of singleton gestations between 18 0/7 and 23 6/7 weeks, without prior sPTB, undergoing universal transvaginal CL screening between 1 January 2012 and 31 December 2013. Only women with sPTB (<37 0/7 weeks) were included. Demographic characteristics, risk factors for sPTB, delivery outcomes and presentation of PTB were collected. The primary outcome was mean number of risk factors.Results: The cohort included 2071 women, of which 145 (7%) had PTB and 84 (4%) had sPTB. Sixty-nine (82%) women with sPTB had a CL >25?mm and 15 (18%) had a CL≤25?mm. Women with a short CL did not differ from women with normal CL with respect to demographic variables or mean number of risk factors (4.20?±?2.11 versus 3.52?±?1.97, p?=?0.23), but they did deliver at a significantly earlier gestational age (25.0?±?1.1 versus 34.6?±?3.1 weeks, p?p?Conclusions: Among women with sPTB, women with a short CL had similar number of risk factors, but were more likely to deliver at a significantly earlier gestational age. A short CL identifies women at risk for very early sPTB. |
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| Keywords: | Cervical length preterm birth |
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