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The outcome of pregnancy with new onset proteinuria without hypertension: retrospective observational study
Authors:Ali Ekiz  Basak Kaya  Ibrahim Polat  Muhittin Eftal Avci  Burak Ozkose  Raziye Kicik Caliskan
Affiliation:1. Department of Obstetrics and Gynaecology, Maternal-Fetal Medicine Unit, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey and draekiz@gmail.com;3. Department of Obstetrics and Gynaecology, Maternal-Fetal Medicine Unit, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey and;4. Department of Obstetrics and Gynaecology, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey
Abstract:Objective: The aim of this study was to evaluate preeclampsia progression of isolated proteinuria and associations with pregnancy outcome.

Method: We performed a retrospective analysis in patients who were hospitalized for evaluation of new onset proteinuria without hypertension after 20 weeks of gestation between January 2012 and January 2014. One hundred fifty-seven patients who met the inclusion criteria were enrolled the study.

Results: After detection of new onset proteinuria, 53 of 157 (33.7%) patients developed preeclampsia and the incidence of gestational proteinuria was found to be 0.33%. Twenty-four hours urine proteinuria testing results were significantly higher in preeclampsia (PE) group compared with the gestational proteinuria (GP) group (p?p?p?Conclusion: The incidence of gestational proteinuria was lower than the previous studies. Preeclampsia developed in 33% of patients with new onset proteinuria in pregnancy. In patients who developed PE had significantly higher proteinuria, lower delivery time and birth weight in their infants. Therefore, patients with new onset proteinuria should be followed-up for preeclampsia development and associated morbidities.
Keywords:Gestational proteinuria  perinatal outcome  preeclampsia
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