Minocycline for the treatment of cutaneous silicone granulomas: A case report |
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| Authors: | Elisete Crocco Mirella Pascini Nathalie Suzuki Renata Alves Thais Proença Rute Lellis |
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| Institution: | 1. Sector of Cosmetic Dermatology, Clinic of Dermatology, Santa Casa de S?o Paulo Hospital and School of Medicine, S?o Paulo-SP, Brazilelisete@elisetecrocco.com.br;3. Specialization program at the Clinic of Dermatology, Santa Casa de S?o Paulo Hospital and School of Medicine, S?o Paulo-SP, Brazil;4. Voluntary program at the Clinic of Dermatology, Santa Casa de S?o Paulo Hospital and School of Medicine, S?o Paulo-SP, Brazil;5. Pathology Department, Santa Casa de S?o Paulo Hospital and School of Medicine, S?o Paulo-SP, Brazil |
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| Abstract: | Silicone oil injections are often used for soft tissue augmentation and local and general adverse effects occurring from a few months to 15 years after injection have been reported. Here, we present a case of delayed granuloma formation due to liquid injectable silicone with large extent of involvement, which precluded surgical removal. Our patient was successfully treated with minocycline, considering its anti-inflammatory, immunomodulating and antigranulomatous properties. This case presents minocycline monotherapy as a useful treatment option for the management of severe granuloma induced by silicone use when surgical excision is not possible. |
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| Keywords: | foreign-body granuloma minocycline silicone oils |
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