| 表皮生长因子对游离毛囊生长的影响 |
| |
| 引用本文： | 杨淑霞,钟志红,秦俭. 表皮生长因子对游离毛囊生长的影响[J]. 中华皮肤科杂志, 2000, 33(2): 99-101 |
| |
| 作者姓名： | 杨淑霞 钟志红 秦俭 |
| |
| 作者单位： | 北京医科大学第一医院皮肤科 |
| |
| 摘 要： | 目的 通过毛囊器官培养观察表皮生长因子（ＥＧＦ）对人头皮毛囊生长的影响。方法 用Ｗｉｌｌｉａｍｓ Ｅ无血清培养基进行人头皮毛囊游离培养，分为２组，ＥＧＦ组（４３根）和对照组（４３根）。结果 ＥＧＦ ２０μｇ／Ｌ组在加药后１～３ｄ毛干平均生长０．２２ｍｍ／ｄ，且平均生长０．１６ｍｍ／ｄ，两组差异有显著性（Ｐ〈０．０５），ＥＧＦ对毛囊生长有更明显的促进作用。但ＥＧＦ组毛囊于培养的第４～６天即出现退行期
|
| 关 键 词： | 毛囊 器官培养 表皮生长因子 尿抑胃素 |
Effects of Epidermal Growth Factor on Human Hair Follicle Growth in vitro |
| |
| YANG Shuxia,ZHONG Zhihong,QIN Jian,et al.. Effects of Epidermal Growth Factor on Human Hair Follicle Growth in vitro[J]. Chinese Journal of Dermatology, 2000, 33(2): 99-101 |
| |
| Authors: | YANG Shuxia ZHONG Zhihong QIN Jian et al. |
| |
| Affiliation: | YANG Shuxia,ZHONG Zhihong,QIN Jian,et al. Department of Dermatology,The First Hospital of Beijing Medical University,Beijing 100034 |
| |
| Abstract: | Objective To investigate the effects of epidermal growth factor (EGF) on hair follicle growth. Methods Cultured human hair follicles were divided into two groups: EGF- treated group (EGF 20 ng/mL) and control group. The length and morphology of follicles were measured by inverted microscope daily. 3H- leucine incorporation and histologic studies were applied. Results The rates of hair shaft and hair follicle elongation significantly increased in the EGF- treated group during day 1 to day 3 in comparison with the control group. Histologically, the cells of the lower outer root sheath were thickened and club hair- like structure was formed. 3H- leucine incorporation showed that the radioactivity in hair follicle epithelium was higher in EGF- treated group (370 c/min)than that in control group(271.14 c/min) (P |
| |
| Keywords: | Hair follicle Organ culture Epidermal growth factor- u rogastrone |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
