沙漠行军血浆热休克蛋白与热应激的关系

目的：探讨沙漠干热环境徒手应激行军者热休克蛋白（HSP27）与机体热应激的关系。方法：对在沙漠干热环境中分别以3．5km/h和5．0km/h速度徒手行军1，2，3h的56名战士和14名对照血浆HSP70和HSP27、心律增值、肛温增值和积热指数等进行了研究。结果：不论是3．5km/h还是5．0km/h徒手行军，各行军时间组HSP70与对照组，各行军时间组间均无显著性差异；各行军时间组HSP27明显高于对照组（P＜0．05），各行军时间组间HSP27均无显著性差异；各行军时间组心率增值、肛温增值和积热指数均与对照有显著性差异（P＜0．05）；3．5km/h行军3h组心率增值明显高于行军2h组（P＜0．05），5．0km/h行军2，3h组积热指数明显高于行军1h组（P＜0．05），行军3h组明显低于行军2h组（P＜0．05）。结论：沙漠干热环境徒手应激行军者血浆HSP27与热应激密切相关，HSP70与热应激关系不大；沙漠热环境热适应锻炼以5．0km/h行军2h为宜。

Study on relation between heat shock proteins and heat stress of marcher in desert

Objective To explore the relation between heat shock proteins and heat stress of marchers without load in dry-heat desert.Methods The plasma HSP70 and HSP27,heart beat,rectal temperature and body heat storage index(BHSI) of 56 marchers and 14 controls were detected.Results Either at the speed of 3.5 km/h or 5.0 km/h,the plasma HSP27 in the marching groups were much more than the control(P<0.05);and the plasma HSP70 in the marching groups were slightly over the control(P>0.05);the heart beat in marching groups were more than the control(P<0.05).BHSIs were much more than the control except that marching for 1 hour at 5.0 km/h.Conclusion There was a close relation between HSP27 and heat stress,and no relation between HSP70 and heat stress without load in dry-heat desert.Therefore,the plasma HSP27 was better than HSP70 in the monitor of heat stress.It was the optimum acclimatization to heat that people march for 2 hours at 5.0 km/h in dry-heat desert.