| 黄甘草异黄酮成分的研究 |
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| 引用本文： | 张聿梅,许旭东,胡碧煌,刘勤,侯翠英,杨峻山.黄甘草异黄酮成分的研究[J].药学学报,1997,32(4):301-304. |
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| 作者姓名： | 张聿梅 许旭东 胡碧煌 刘勤 侯翠英 杨峻山 |
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| 作者单位： | 中国医学科学院中国协和医科大学药用植物研究所 |
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| 摘 要： | 从黄甘草(Glycyrrhiza eurycarpa P.C.Li)根及根茎中分得五个异黄酮化合物,根据理化性质及光谱(UV,MS,1HNMR,13CNMR,NOE,HMBC)数据分析,化合物I的结构推定为7,2′,4′-三羟基-3′-异戊烯基异黄酮,为一新化合物,命名为黄甘草异黄酮A(eurycarpinA)。化合物I的结构推定为7,2′-二羟基-(2″,3″∶4′,3′)-6″,6″-二甲基吡喃异黄酮,为一新的天然产物,命名为黄甘草异黄酮B(eurycarpinB)。其余化合物分别鉴定为 licoisoflavone A(III),毛蕊异黄酮(calycosin,IV)和芒柄花素(formononetin,V)。化合物II～V均为首次从本植物中得到。
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| 关 键 词： | 黄甘草 异黄酮 黄甘草异黄酮A 黄甘草异黄酮B |
| 收稿时间： | 1996-01-31 |
ISOFLAVONES FROM GLYCYRRHIZA EURYCARPA |
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| YM Zhang,XD Xu,BH Hu,Q Liu,CY Hou,YL Liu and JS Yang.ISOFLAVONES FROM GLYCYRRHIZA EURYCARPA[J].Acta Pharmaceutica Sinica,1997,32(4):301-304. |
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| Authors: | YM Zhang XD Xu BH Hu Q Liu CY Hou YL Liu and JS Yang |
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| Institution: | Institute of Medicinal Plant, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100094. |
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| Abstract: | A new isoflavone, named eurycarpin A and a new natural product isoflavone named eurycarpin B have been isolated from the roots of Glycyrrhiza eurycarpa P. C. Li. Their structures were determined to be 7,2',4'-trihydroxy-3'-(3,3-dimethylallyl) isoflavone(I) and 7,2'-dihydroxy-6",6"-dimethylpyrano-(2",3":4',3') isoflavone(II) on the basis of spectroscopic analysis (UV, EI-MS, 1HNMR, 13CNMR, NOE difference and HMBC). In addition, three known isoflavones, licoisoflavone A, calycosin and formononetin, were obtained for the first time from this plant. |
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| Keywords: | Glycyrrhiza eurycarpa Isoflavone Eurycarpin A Eurycarpin B |
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