| 吸烟对人末梢血淋巴细胞微核和核形态的影响 |
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| 引用本文： | 徐厚铨,梁永慧,丁恬,杨志祥,粘翠彬. 吸烟对人末梢血淋巴细胞微核和核形态的影响[J]. 山东大学学报(医学版), 1990, 0(3) |
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| 作者姓名： | 徐厚铨 梁永慧 丁恬 杨志祥 粘翠彬 |
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| 作者单位： | 山东医科大学环境卫生学教研室，山东医科大学环境卫生学教研室，山东医科大学环境卫生学教研室，山东医科大学环境卫生学教研室，济南市教育学院 |
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| 摘 要： | 用人体末梢血微核测试法对吸烟支数不同的178名男性教师进行生物材料监测,观察人体末梢血淋巴细胞微核和核变形。结果表明不吸、偶吸和现吸3组间在3项微核指标与5项核变形指标上有显著性或非常显著性差异、吸烟量与淋巴细胞微核3项指标之间存在明显的剂量-反应关系。
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| 关 键 词： | 吸烟 淋巴细胞 微核 核变形 |
EFFECTS OF SMOKING ON MICRONUCLEUS AND NUCLEAR FORMATION IN HUMAN LYMPHOCYTES |
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| Xu Houquan,et al Dept.of Environmental Hygiene,Shandong Medical University. EFFECTS OF SMOKING ON MICRONUCLEUS AND NUCLEAR FORMATION IN HUMAN LYMPHOCYTES[J]. Journal of Shandong University:Health Sciences, 1990, 0(3) |
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| Authors: | Xu Houquan et al Dept.of Environmental Hygiene Shandong Medical University |
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| Abstract: | The genotoxic effect of smoking was studied employing micro-nucleus test by human skin puncture and examining micronuclei and nu-clear formation in human lymphocytes among 178 male teachers aged 20years and over.Frequency of micronucleus(MNF),frequency of cell micro-nuclei(CMF),rate of micronucleus men(MMR)and frequency of irreg-ular nucleus(INF)was detected among current-smokers and accidental-smokers and nonsmokers.The result was established that significance andhighly significance difference observed by statistical treatment.Relation ofdose-response was established between smoking amount and micronucleinumber.Indices of micronuclei and nuclear anomaly might be useful instudying smoking induced mutagenesis. |
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| Keywords: | Smoking Lymphocytes Micronucleus Irregular nucleus |
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