氩氦刀治疗胸部肿瘤的临床应用

目的：探讨CT定位导引下氩氦刀治疗胸部肿瘤的可行性、安全性及疗效评价。方法：36例经病理证实的胸部肿瘤（41处病灶）在CT定位导引下经皮行氩氦刀冷冻消融治疗，术后计算冰球覆盖率，统计数据采用x2检验进行差异显著性检验，P＜0．05认为差异有显著性。结果：冷冻消融治疗后，胸部肿瘤病灶呈球形低密度，CT值均明显下降；最大径小于3cm、3cm～5cm、大于5cm的肿瘤冰球覆盖率分别为96．3±1．9、84．2±2．8、60．1±3．6，前2组与第3组的冰球覆盖率差异有统计学意义（P＜0．05）；并发症发生率13．8％（5/36）：其中气胸3例，肺出血2例。结论：氩氦刀冷冻消融治疗胸部肿瘤是一种安全、有效的治疗方法，治疗效果明显，在CT准确定位下，手术并发症发生率低，具有较高的临床应用价值。

Therapeutic Application of thoracic neoplasm by Argon-helium Cryosurgery system

Purpose：To investigate the feasibility, safety and efficacy evaluation for the treatment of thoracic neoplasm by CT guided AHCS （argon-helium cryosurgery system）.Methods：36 patients （41 lesions） with pathologically confirmed thoracic neo-plasm were treated in CT guided AHCS and then calculated ice hockey coverage ratio.All statistical data were analyzed mainly through the x2 test.Difference were considered to be statistically significant if P〈0 .05 .Results：After cryoablation therapy, breast neoplasm were spherical with low density, the CT values were significantly decreased.The maximum tumor diameter of less than 3cm,3cm ~5cm, greater than 5cm hockey coverage rate was 96.3 ±1.9, 84.2 ±2.8, 60.1 ±3.6,respectively Hockey coverage of the first two groups and the third group difference was statistically significant （P〈0.05）.Complication rate of 13.8%（5/36）：pneumothorax in 3 cases, pulmonary hemorrhage in 2 cases.Conclusion：The treatment of thoracic neoplasm by CT guided AHCS might be a safe and effective method of treatment, the accurate positioning of the CT-Pinpoint location system, the low incidence of complications, with a high clinical value.