噻托溴铵辅助治疗慢性阻塞性肺疾病的疗效评价

目的：探讨噻托溴铵辅助治疗慢性阻塞性肺疾病的疗效。方法：慢性阻塞性肺疾病患者80例，随机分为治疗组与对照组，各40例。对照组采用常规综合疗法，治疗组在此基础上给予噻托溴铵辅助治疗。结果：治疗后治疗组的FEV1、FEV1／FVC与PEF值明显高于对照组，差异有统计学意义（P〈0．05）。对照组出现口干1例，尿潴留1例；治疗组出现口干2例，尿潴留1例。2组不良反应对比差异无统计学意义（P〉0．05）。结论：吸入噻托溴铵辅助治疗慢性阻塞性肺病患者能有效改善肺功能，不良反应少，值得临床推广应用。

Evaluation of Effect of Tiotropium Bromide in Adjuvant Treatment of Chronic Obstructive Pulmonary Disease

Objective：To explore the effect of Tiotropium Bromide in adjuvant treatment of chronic obstructive pulmonary disease. Methods ：80 samples were randomly divided into the treatment group and the control group of 40 cases respectively. The control group was treated with routine treatment and the treatment group was added to Tiotropium Bromide. Results：The FEV1, FEV1/FVC ,and PEF of the treatment group was higher than the control group after treatment, and the difference was statistically significant （ P 〈 0.05）. There were 1 patient with xerostomia and 1 patient with uroschesis in the control group , and 2 patients with xerostomia and 1 patient with uroschesis in the treatment group. It was no statistically significant difference （P 〉 0.05）. Conclusion：h is worth to populate and apply that Tiotropium Bromide in adjuvant treatment of chronic obstructive pulmonary disease may be useful and safe.