| 基于局部一致性(ReHo)方法的慢性吸烟静息状态功能磁共振(fMRI)研究 |
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| 引用本文： | 廖艳辉,唐劲松,邓奇坚,张燕,罗涛,王绪轶,湛红献,向小军,刘铁桥,陈晓岗,郝伟.基于局部一致性(ReHo)方法的慢性吸烟静息状态功能磁共振(fMRI)研究[J].中国临床心理学杂志,2011,19(4):427-429,436. |
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| 作者姓名： | 廖艳辉 唐劲松 邓奇坚 张燕 罗涛 王绪轶 湛红献 向小军 刘铁桥 陈晓岗 郝伟 |
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| 作者单位： | 中南大学湘雅二医院精神卫生研究所,湖南,长沙,410011 |
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| 基金项目： | 国家"十一五"支撑课题，国家自然科学基金，973课题，湖南省自然基金课题 |
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| 摘 要： | 目的:探讨慢性吸烟者静息状态下的脑功能活动情况。方法:采用局部一致性(ReHo)方法,对44名慢性吸烟者和44名与之相匹配的不吸烟的健康志愿者在静息状态下脑功能活动情况进行比较分析。结果:与不吸烟者相比,慢性吸烟者静息状态右侧额下回BOLD信号ReHo降低,左侧顶上回BOLD信号ReHo增强(P<0.05,纠正后,cluster水平)。结论:研究结果提示慢性吸烟会导致额叶和顶叶脑区功能活动的改变。
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| 关 键 词： | 慢性吸烟 静息状态 功能磁共振 局部一致性 |
A Study of Resting State Functional Magnetic Resonance Imaging(fMRI) in Chronic Cigarette Smoking Using ReHo |
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| LIAO Yan-hui,TANG Jin-song,DENG Qi-jian,et al Mental Health Institute,Second Xiangya Hospital,Central South University,Changsha ,China.A Study of Resting State Functional Magnetic Resonance Imaging(fMRI) in Chronic Cigarette Smoking Using ReHo[J].Chinese Journal of Clinical Psychology,2011,19(4):427-429,436. |
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| Authors: | LIAO Yan-hui TANG Jin-song DENG Qi-jian Mental Health Institute Second Xiangya Hospital Central South University Changsha China |
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| Institution: | LIAO Yan-hui,TANG Jin-song,DENG Qi-jian,et al Mental Health Institute,Second Xiangya Hospital,Central South University,Changsha 410011,China |
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| Abstract: | Objective: To assess the alterations in regional homogeneity(ReHo) of resting-state brain activity in chronic cigarette smokers.Methods: 45 otherwise healthy smokers and 44 healthy control subjects were imaged with BOLD fMRI and analyzed with the ReHo method.Results: Compared with healthy controls,decreased ReHo was found in smokers in the right inferior frontal gyrus and increased ReHo was found in left superior parietal lobule(P<0.05,voxel=10,cluster-level corrected).Conclusion: Our findings indicates abn... |
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| Keywords: | Chronic cigarette smoking Resting state Functional magnetic resonance imaging Regional homogeneity |
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