CT引导下125I粒子植入联合经皮椎体成形术治疗椎体转移性肿瘤

目的:探讨CT引导下125I粒子植入联合经皮椎体成形术(PVP)治疗椎体转移性肿瘤的临床价值.方法:15例患者共累及22节椎体,1～3节/倒,其中颈椎1节、胸椎11节,腰椎10节.所有病例均在CT 引导下采用粒子针直接穿刺或粒子针通过骨水泥针同轴技术进行125I粒子植入,并采用粒子针或联合骨水泥针完成PVP治疗.结果:...

The combined treatment of CT-guided radioactivie 125 I-seed implantation and percutaneous vertebroplasty for vertebral metastases

Objective：To evaluate efficiency of a combined treatment consisting of CT-guided radioactive 125I-seed im- plantation （CTRISI） with percutaneous vertebroplasty （PVP） for vertebral metastases. Methods：Fifteen patients with ver- tebral metastases received a combination treatment of CTRISI and PVP. The treatments were performed with seed needles alone or followed by hone cement needles. Results：Of all the 22 spinal lesions,the thoracic area （n= 11） of the spine is the most affected, followed by lumbar （n= 10） and cervical （n= 1）. 100% of the patients achieved successful treatment. The number of 125I seeds per vertebra ranged from 6 to 30. The average volume of injected bone cement was 1.5 46.0ml per ver- tebra. The procedures could be achieved with seed needle alone in 20 （91%） vertebrae and followed by bone cement needle in 2 vertebrae. 86.7 % of the patients had significant pain relief. There is no major complications, such as spinal cord compression, radiation injuries, except for leak of bone cement. Conclusion：The combined treatment of CTRISI and PVP is a safe and effective method for treating patients with vertebral metastases.