| 新生儿HIE脑水肿的发生机制及其DWI、DTI特征与AQP-4的相关性 |
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| 引用本文： | 王宏伟 综述,王晓明,郭启勇 审校. 新生儿HIE脑水肿的发生机制及其DWI、DTI特征与AQP-4的相关性[J]. 中国医学影像技术, 2008, 24(4): 622-625 |
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| 作者姓名： | 王宏伟 综述 王晓明 郭启勇 审校 |
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| 作者单位： | 中国医科大学附属盛京医院放射科,辽宁,沈阳,110004 |
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| 摘 要： | 脑水肿是新生儿缺氧缺血性脑病的早期病理生理学改变,DWI、DTI可以准确监测脑水肿的影像信号变化过程。近来研究表明AQP-4与脑水肿关系密切,并与新生儿HIE脑水肿的DWI、DTI表现相关联。现对AQP-4与新生儿HIE脑水肿的发生机制及其DWI、DTI特征的相关性进行综述。
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| 关 键 词： | 缺氧缺血性脑病 水通道蛋白-4 扩散加权成像 扩散张量成像 新生儿 脑水肿 发生机制 特征 相关性 mechanism Relation neonate brain edema 关联 表现 关系 研究 变化过程 影像信号 监测 学改 病理生理 早期 缺血性脑病 |
| 文章编号： | 1003-3289(2008)04-0622-04 |
| 收稿时间： | 2007-07-15 |
| 修稿时间： | 2007-08-02 |
Relation between the mechanism and DWI, DTI features of brain edema and AQP-4 in neonate with HIE |
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| WANG Hong-wei,WANG Xiao-ming and GUO Qi-yong. Relation between the mechanism and DWI, DTI features of brain edema and AQP-4 in neonate with HIE[J]. Chinese Journal of Medical Imaging Technology, 2008, 24(4): 622-625 |
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| Authors: | WANG Hong-wei WANG Xiao-ming GUO Qi-yong |
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| Affiliation: | Department of Radiology, Shengjing Hospital, China Medical University, Shenyang 110004, China;Department of Radiology, Shengjing Hospital, China Medical University, Shenyang 110004, China;Department of Radiology, Shengjing Hospital, China Medical University, Shenyang 110004, China |
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| Abstract: | Brain edema is one of the early symptoms of HIE. DWI and DTI are very efficient in detecting the signal changing of brain edema. It is recently indicated that AQP-4 shows close relation with brain edema, and with DWI, DTI features of brain edema in neonate with HIE. This review summarises the relation between the mechanism and DWI, DTI features of brain edema and AQP-4 in neonate with HIE. |
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| Keywords: | Hypoxic ischemic encephalopathy AQP-4 Diffusion-weighted imaging Diffusion tensor imaging |
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