缺血性卒中相关性肺炎危险因素分析

目的 分析缺血性卒中相关性肺炎危险因素。 方法 连续入组2014年5月-2016年5月收治的急性缺血性卒中患者为研究对象，根据是否在卒中发 病7 d内新发生肺炎将患者分为无卒中相关性肺炎组与卒中相关性肺炎组，比较两组患者的血管危险 因素、入院NIHSS等指标的差异，并采用多因素logistic回归分析卒中相关性肺炎的独立影响因素。 结果 研究共入组1129例急性缺血性卒中患者，无卒中相关性肺炎组1043例，卒中相关性肺炎组86 例。多因素分析显示，年龄增高（OR 1.084，95%CI 1.047～1.122，P <0.0001）、入院NIHSS评分增加（OR 1.192，95%CI 1.133～1.254，P <0.0001）、白细胞计数升高（OR 1.269，95%CI 1.134～1.420，P <0.0001） 及住院天数延长（OR 1.146，95%CI 1.087～1.208，P <0.0001）是卒中相关性肺炎的独立危险因素。 结论 缺血性卒中后卒中相关性肺炎的发生与高龄、神经功能缺损程度重、白细胞增高、住院时间 长有关。

Analysis of Risk Factors for Ischemic Stroke-associated Pneumonia

Objective To analyze the risk factors for stroke-associated pneumonia.Methods The patients with acute ischemic stroke(AIS)who were consecutively admitted to Beijing Tiantan Hospital from May 2014 to May 2016 were included in this retrospective study.According to whether they developed new-onset pneumonia within 7 days of stroke onset,all the patients were divided into stroke-associated pneumonia group and non-pneumonia group.The vascular risk factors and NIHSS at admission were compared between the two groups,and multivariate logistic regression analysis was used to analyze the risk factors for stroke-associated pneumonia.Results A total of 1129 patients were included,including 1043 patients in non-pneumonia group and 86 patients in stroke-associated pneumonia group.Multivariate analysis showed that elder age(OR 1.084,95%CI 1.047-1.122,P<0.0001),NIHSS at admission(OR 1.192,95%CI 1.133-1.254,P<0.0001),increased white blood cells count(OR 1.269,95%CI 1.134-1.420,P<0.0001)and long hospital stay(OR 1.146,95%CI 1.087-1.208,P<0.0001)were independent risk factors for strokeassociated pneumonia.Conclusions Acute ischemic stroke-associated pneumonia were associated with elder age,severe neurological impairment,increased white blood cells count and long hospital stay.