青中年时期体重状态变化与中老年时期高血压的关系

目的:探讨青年及中年时期超重后的体重状态变化及减重比与中老年高血压患病风险的关系。方法:选取中国糖尿病和代谢紊乱研究中年龄40～79岁的人群。减重比定义为(最大体重-目前体重)/最大体重。采用多因素 logistic回归分析，分别探讨青年及中年超重后的体重状态变化及减重比与高血压的关系。 结果:共...

Relationship between changes of body weight status in young and middle-aged and hypertension in middle-aged and elderly people

Objective To investigate the relationship between changes of weight status after becom-ing overweight in young adults and middle-aged and weight loss ratio and the risk of hypertension in middle-aged and elderly population.Methods Participants aged 40-79 years old were selected from China NationalDiabetes and Metabolic Disorders Survey.Weight loss ratio was defined as(maximum weight-currentweight)/maximum weight.The association between changes of weight status after becoming overweight inyoung adults and middle-aged and weight loss ratio and the risk of hypertension was examined by using multivari-ate logistic regression.Results A total of 7623 cases of hypertension were diagnosed among 19823 studyparticipants.(1)Compared with normal weight group(18.5 kg/m²≤both MAXBMI and BMI<24.0 kg/m²),theOR(95%CI)of hypertension for continuous overweight group from young adults(both MAXBMI and BMI≥24.0 kg/m,18 years≤age of maximum weight<40 years),continuous overweight group from middle-aged(both MAXBMI and BMI≥24.0 kg/m²,40 years≤age of maximum weight<60 years)were 2.66(2.38-2.96)and 2.79(2.56-3.03),and the OR(95%CI)for past overweight from young adults(MAXBMI≥24.0 kg/m²,18.5 kg/m²≤BMI<24.0 kg/m²,18 years≤age of maximum weight<40 years),past over-weight from middle-aged(MAXBMI≥24.0 kg/m²,18.5 kg/m²≤BMI<24.0 kg/m2,40 years≤age of maximum weight<60 years)were 1.20(1.04-1.37)and 1.58(1.40-1.78).(2)Compared with weightloss ratio<5%,weight loss ratio≥5%was associated with decreased risk of hypertension in normal weight(18.5 kg/m²≤MAXBMI<24.0 kg/m²)and overweight(MAXBMI≥24.0 k/m²)population.Conclu-sion Overweight in young adults and middle-aged is associated with increased risk of hypertension in mid-dle-aged and aged population regardless of current BMI.Weight loss of 5%or more from maximum bodyweight may be a protective factor against hypertension regardless of MAXBMI.