| 预报静脉血药浓度的药动学模型C |
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| 引用本文： | 杨静化,宋祥珍.预报静脉血药浓度的药动学模型C[J].中国药科大学学报,1997,28(1):59-62. |
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| 作者姓名： | 杨静化 宋祥珍 |
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| 作者单位： | [1]数学教研室 [2]南京市药品检验所 |
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| 摘 要： | 文中建立的马尔可夫模型是研究血液沿静脉、肺、动脉通过器官回到静脉的循环过程中，血药浓度的变化规律。该模型综合了生理药学模型和主心模型的优点，并提出了血药浓度衰减的频率因子。．
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| 关 键 词： | 药代动力学 生物药动学模型 静脉血药浓度 |
The Markovian Model C in Pharmacokinetics |
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| Yang Jinghu,Song Xiangzheng.The Markovian Model C in Pharmacokinetics[J].Journal of China Pharmaceutical University,1997,28(1):59-62. |
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| Authors: | Yang Jinghu Song Xiangzheng |
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| Institution: | Yang Jinghu,Song Xiangzheng Department of Mathematics,China Pharmaceutical University,Nanjing,Nanjing Institute of Drug Control,Nanjing |
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| Abstract: | The Markovian model C developed in this paper is applicable for the calculation of the blood concentration in the organs, such as vein,lung and artery.It has the advantage of physiological pharmacokinetics model,its kinetic parameters have anatomic and physiological meanings, and its solution can be expressed succinctly like the atrium model. |
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| Keywords: | Physiological pharmacokinetics model Markovian model |
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