Leucocyte migration inhibition in diphtheria toxoid hypersensitivity |
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| Authors: | M. F. Saxby M. R. Salaman I. L. Sargent |
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| Affiliation: | Department of Immunology, St. Mary's Hospital Medical School, London, U.K. |
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| Abstract: | A donor who was highly reactive to diphtheria toxoid (DT) in delayed hypersensitivity and in lymphocyte transformation showed scant evidence of antigen-induced inhibition in the direct leucocyte migration agarose test. Other donors, weak or negative to DT in skin test and transformation, did show evidence of inhibition. Although the migration test is useful in assessing cellular reactivity to tubercular antigen, these results question its suitability for DT. |
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| Keywords: | diphtheria toxoid leucocyte migration inhibition lymphocyte transformation tuberculin |
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